CompBioClub

Welcome to CompBioClub! We are a group of computational biologists studied and worked at the Department of Biomedical Science, City University of Hong Kong. Led by Dr. Lingxi Chen, it’s as if the Monkey Kings/Queens wield computer science and AI like a golden cudgel, navigating the vast ocean of biomedical science to ultimately uncover the true scripture of knowledge (Image credited to パプリカ).

Hiring

We are seeking talented and passionate Research Assistants and PhD candidates.

Research Interests

Single-Cell and Spatial Omics: To design computational algorithms tailored for the analysis of bulk, single-cell, and spatial omics data. To address the challenges such as imputing missing data, dimension reduction, clustering, data integration, and more.
Genomic Structural Aberrations: To develop specialized tools for the detection and analysis of genomic aberrations, such as single nucleotide variations (SNVs), copy number variations (CNVs), and complex structural variations (CSVs). To identify the aberration biomarkers associated with multiple cancers and complex diseases for precision medicine.
AI in Healthcare: To build diagnostic and prognostic AI models for various conditions, including cancer and complex diseases in humans and animals.
Online Biomedical Platforms: To create user-friendly online webservers and databases that offer integrated analysis pipelines and interactive visualization interfaces. To enable non-bioinformaticians to explore complex biological data with simple mouse operations.

news

Jan 15, 2016	A simple inline announcement with Markdown emoji!
Nov 07, 2015	A long announcement with details
Oct 22, 2015	A simple inline announcement.

Selected Publications

PhysRev

Can Quantum-Mechanical Description of Physical Reality Be Considered Complete?

A. Einstein^*†, B. Podolsky^*, and N. Rosen^*

Phys. Rev., New Jersey. More Information can be found here , May 1935

Abs HTML PDF Video

In a complete theory there is an element corresponding to each element of reality. A sufficient condition for the reality of a physical quantity is the possibility of predicting it with certainty, without disturbing the system. In quantum mechanics in the case of two physical quantities described by non-commuting operators, the knowledge of one precludes the knowledge of the other. Then either (1) the description of reality given by the wave function in quantum mechanics is not complete or (2) these two quantities cannot have simultaneous reality. Consideration of the problem of making predictions concerning a system on the basis of measurements made on another system that had previously interacted with it leads to the result that if (1) is false then (2) is also false. One is thus led to conclude that the description of reality as given by a wave function is not complete.